RNA Details
Disease Name
diabetic kidney disease
Tissue
kidney
RNA Symbol
miR-154-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
rattus norvegicus
Detection Methods
bioinformatics predicted binding sites;luciferase;Co-IP etc.
Target
Smurf1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
miR-154-5p Affects the TGF beta 1/Smad3 Pathway on the Fibrosis of Diabetic Kidney Disease via Binding E3 Ubiquitin Ligase Smurf1
Year
2022
Function
MiR-154-5p regulates the TGF beta1/Smads pathway through Smurf1 ubiquitination and promotes the fibrosis process of diabetic kidney disease.